Thursday, March 4, 2010

What are the Causes of Breast Fibroids?

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Thursday, January 7, 2010, 15:52
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Breast fibroids, also known as fibrocystic breast disease, fibroid breasts, mammary dysplasia, benign breast disease and diffuse cystic mastopathy, are benign (non-cancerous), moveable, rubbery nodules that cause painful swelling near the breast surface.

GEL INJECTION APPARATUS AND TREATMENT OF BREAST, FIBROIDS AND ENDOMETRIAL ABLATION
An injection apparatus for treatment of diseases associated with female reproductive organs, comprising: a hollow core needle with a distal tip; an access probe configured to provide access to a uterus cavity by way of a vaginal canal; a lumen in the access probe for guiding said needle, the access probe adapted for directing the distal tip to a tissue area of interest selected from the group consisting of uterus, fibroid, myoma, fallopian tube, ovary, and cervix; and an injector for delivering a treatment substance comprising an active treatment substance and an inactive binding substance through the needle to the tissue area of interest.

Breast Cancer Drug Effective for Fibroids in Women

In premenopausal women with fibroids, the breast cancer drug anastrozole (Arimidex) reduces fibroid size and improves bothersome symptoms, according to results of a prospective study conducted at the Aristotle University of Thessaloniki in Greece.
Fibroid tumors, or uterine leiomyomata, are benign growths in the uterus that can cause pain and bleeding and may eventually require surgical removal.

Based on other studies, the researchers think long-term treatment with anastrozole will be safe, but they emphasize that larger, placebo-controlled clinical trials will be required to establish the risk posed by prolonged anastrazole use in premenopausal women.

Anastrozole is typically prescribed for older (postmenopausal) women with breast cancer that is sensitive to estrogen. Anastrozole, and similar drugs, inhibit the enzyme aromatase, which is needed to produce estrogen. The current study suggests that anastrozole, given in such a low dose, acts primarily by blocking estrogens produced by the fibroids.

What are the Causes of Breast Fibroids?
The causes of breast fibroids are not completely understood. However, there are several factors that play a significant role in the development of the disease.

·    The monthly changes in the levels of oestrogen and progesterone are considered to be the most noteworthy factors contributing to this disease. These two hormones directly affect the breast tissues by causing cells to grow and multiply.
·    Prolactin, growth factor, thyroid hormone and insulin also influence the development of breast fibroids.
·    The breast produces hormonal products from its glandular and fat cells. These hormonal products send signals to the neighbouring breast cells. These signals are the key factors responsible for the development of breast fibroids.

Difference between benign breast lumps and cancerous ones

Uterine fibroids (singular Uterine Fibroma) (leiomyomata, singular leiomyoma) are benign tumors which grow from the muscle layers of the uterus.Fibroids are named according to where they are found. They are the most common benign neoplasm in females, and may affect about 25% of white and 50% of black women during the reproductive years. Uterine fibroids shrink dramatically in size after a woman passes through menopause. Cervical fibroids are found in the wall of the womb and can become very large.

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